(1,2,3,4-tetrahydroquinolin-6-yl)boronic acid
(1-(tert-Butoxycarbonyl)-1,2,3,4-tetrahydroquinolin-6-yl)boronic acid
CAS: 1260150-04-6
Molecular Formula: C14H20BNO4
(1,2,3,4-tetrahydroquinolin-6-yl)boronic acid - Names and Identifiers
(1,2,3,4-tetrahydroquinolin-6-yl)boronic acid - Physico-chemical Properties
| Molecular Formula | C14H20BNO4 |
| Molar Mass | 277.12 |
| Density | 1.21±0.1 g/cm3(Predicted) |
| Melting Point | >120°C (dec.) |
| Boling Point | 453.3±55.0 °C(Predicted) |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Appearance | Solid |
| Color | Off White to Pale Green |
| pKa | 8.74±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | IRRITANT |
| MDL | MFCD06801709 |
(1,2,3,4-tetrahydroquinolin-6-yl)boronic acid - Introduction
(1-(tert-Butoxycarbonyl)-1,2,3,) boronic acid is a compound with the chemical formula C16H23BN2O4.
Nature:
(1-(tert-Butoxycarbonyl)-1,2,3) boronic acid is a white solid, soluble in some common organic solvents, such as dimethyl sulfoxide, dimethylformamide and acetonitrile. It has high thermal stability under normal conditions.
Use:
(1-(tert-Butoxycarbonyl)-1,2,3) boronic acid is an organic boron compound, which is widely used in organic synthesis. It can be used as an effective boron reagent to participate in the synthesis reactions such as Lin and phenyl reaction, diazotization reaction, aldehyde nucleophilic addition reaction, C- H bond functionalization, etc. It plays an important role in the construction of organic molecular framework and the synthesis of organic compounds.
Preparation Method:
(1-(tert-Butoxycarbonyl)-1,2,3) boronic acid can be obtained by reacting phenylboronic acid or other boron reagents with 1-(tert-butylperoxycarbonyl) tetrahydroquinoline. The reaction is usually carried out under an inert atmosphere at room temperature to the boiling point of the reactants, and the reaction time is relatively long.
Safety Information:
(1-(tert-Butoxycarbonyl)-1,2,3,) boronic acid has no obvious toxicity to human body under normal conditions, but it still needs to be used carefully. Appropriate protective measures, including gloves, goggles and protective clothing, should be taken during manipulation. At the same time, it should be ensured that the operation is carried out in a well-ventilated environment. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
Please note that the above information is for reference only. The specific experimental operation and safety precautions should also follow the relevant laboratory rules and regulations and professional knowledge.
Nature:
(1-(tert-Butoxycarbonyl)-1,2,3) boronic acid is a white solid, soluble in some common organic solvents, such as dimethyl sulfoxide, dimethylformamide and acetonitrile. It has high thermal stability under normal conditions.
Use:
(1-(tert-Butoxycarbonyl)-1,2,3) boronic acid is an organic boron compound, which is widely used in organic synthesis. It can be used as an effective boron reagent to participate in the synthesis reactions such as Lin and phenyl reaction, diazotization reaction, aldehyde nucleophilic addition reaction, C- H bond functionalization, etc. It plays an important role in the construction of organic molecular framework and the synthesis of organic compounds.
Preparation Method:
(1-(tert-Butoxycarbonyl)-1,2,3) boronic acid can be obtained by reacting phenylboronic acid or other boron reagents with 1-(tert-butylperoxycarbonyl) tetrahydroquinoline. The reaction is usually carried out under an inert atmosphere at room temperature to the boiling point of the reactants, and the reaction time is relatively long.
Safety Information:
(1-(tert-Butoxycarbonyl)-1,2,3,) boronic acid has no obvious toxicity to human body under normal conditions, but it still needs to be used carefully. Appropriate protective measures, including gloves, goggles and protective clothing, should be taken during manipulation. At the same time, it should be ensured that the operation is carried out in a well-ventilated environment. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
Please note that the above information is for reference only. The specific experimental operation and safety precautions should also follow the relevant laboratory rules and regulations and professional knowledge.
Last Update：2024-04-10 22:29:15
